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Actilax

Size: 100ml

Generic Name: Lactulose

FDA Classification: Laxative

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Actilax is indicated for

  • The treatment of constipation
  • The treatment of hepatic encephalopathy (HE); hepatic coma
  • Actilax may be administered diluter or undiluted. Each dose may, if necessary, be taken with water or fruit juices, etc. Each dose of lactulose should be swallowed in one and should not be kept in the mouth for an extended period of time
  • The dosage should be adjusted according to the individual needs of the patient. In case of a single daily dose, this should be taken at theme time, e.g. during breakfast. During therapy with laxatives, it is recommended to drink sufficient amounts of fluids (1.5-2 liters, equal to 6-8 glasses) during the day
  • Dosing in constipation – lactulose is given as a single daily dose or in two divided doses. After a few days, the starting dosage may be adjusted to the maintenance dose based upon treatment response. Several days (2-3 days) of treatment may be needed before treatment effect occurs 
    Starting dose (daily) Maintenance dose (daily)
    Adults & adolescents 15-45mL 15-30mL
    Children (7-14 years) 15mL 10-15mL
    Children (1-6 years) 5-10mL 5-10mL
    Infants under 1 year Up to 5mL Up to 5mL

     

  • Dosing in Hepatic Encephalopathy 
    • Adults – starting dose: 3 to 4 times daily at 30-45mL. The dose may be adjusted to the maintenance dose to achieve two or three soft stools each day
    • Special populations
      • Pediatric populations – the safety and efficacy in children (newborn to 18 years of age) with HE have not been established. No data are available. For precise dosing for infants and children up to 7 years, lactulose in bottles should be used
      • Elderly patients and patients with renal and hepatic insufficiency – No special dosage recommendation exists, since systemic exposure to lactulose is negligible
  • Availability – Opaque White PET Bottle x 100 mL (Box of 1’s)
  • Manufacturer – Zee Laboratories 
  • Importer/Distributor – EON Pharmatek Inc.
Preservative Free
Each mL contains: Lactulose USP 270mg

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