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Fleozol

Size: 150mg/200mg

Generic Name:  Fluconazole

FDA Classification: Rx (Prescription Drug)

 

 

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Fluconazole (FLEOZOL) 150mg capsule is indicated for

  • Mucosal candidiasis e.g. oropharyngeal, esophageal, mucocutaneous and chronic oral atrophic candidiasis, vaginal candidiasis etc.
  • Systemic candidiasis: Candidaemia, disseminated candidiasis, infection fo the peritoneum, endocardium, pulmonary and urinary tract
  • Cryptococcosis: cryptococcal meningitis, primary as well as maintenance therapy
  • Prevention of Fungal infection: In patients with malignancy, AIDS, in intensive care units and patients on immunosuppresive drugs
  • Adults 
    • oropharyngeal candidiasis – 200mg on the first day, then followed by 100mg once daily for 14 days
    • Esophageal candidiasis – 200mg on the first day, followed by 100mg once daily for 21 days
    • Vaginal candidiasis – 150mg as a single dose
    • Cryptococcal meningitis – 400mg loading dose, followed by 200mg daily for 10-12 weeks after CFS becomes culture negative
    • Maintenance to prevent relapse of cryptococcus meningitis: 100-200mg daily
    • Prophylaxis in immunocompromised – 50-400mg once daily started several days before onset of neutropenia and continues for 7 days after neutrophil count > 1000 cell/mm3
  • Children
    • Mucosal candidiasis
      • < 2 weeks – 3mg/kg every 72 hrs
      • 2-4 weeks – 3mg/kg every 48 hrs
      • > 4 weeks – 3mg/kg daily
    • Systemic candidiasis
      • < 2 weeks – 6-12mg/kg every 72 hrs
      • 2-4 weeks – 6-12mg/kg every 48 hrs
      • > 4 weeks – 6-12mg/kg daily
    • Prophylaxis in immunocompromised
      • < 2 weeks – 3-12mg/kg every 72 hrs
      • 2-4 weeks – 3-12mg/kg every 48 hrs
      • > 4 weeks – 3-12mg/kg daily
  • In impaired renal function
    • Fluconazole is excreted predominantly in urine as unchanged drug. Hence, in patients with impaired renal function, dosage of fluconazole must be modified in response to the degree of impairment
    • The recommended dosages are:
      CREATININE CLEARANCE (mL/min) DOSAGE INTERNAL/DAILY DOSE
      >50

      21-50

      10-20

      Patients receiving regular hemodialysis

      		 24hrs/100%

      48hrs/50%

      72s/25%

      100 percent dose after every dialysis

 

Availability

Alu/PVC Blister Pack x 1’s (Box of 10’s)

Alu/PVC Blister Pack x 10’s (Box of 10’s and 100’s)

 

Manufacturer: 

Zee Laboratories

 

Importer/Distributor: 

EON Phamatek Inc.

Preservative Free
Each capsule contains: Fluconazole USP 150mg

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