Articles > Why Series > Why Adfer for Pregnant women? 
Why Adfer for Pregnant women? 
 
Adfer (Carbonyl iron) is more effective in the treatment of iron deficiency anemia in pregnant women as compared to the conventional iron formulations because of its superior efficacy in elevating haemoglobin levels as well as it is better tolerated than other iron formulations.
Study Background 
 
The requirements of iron increase during pregnancy, as in the third trimester, a pregnant woman needs six times more iron than a nonpregnant woman. Increased iron requirements to supply the expanding blood volume of the mother and the rapidly growing fetus and placenta can cause iron deficiency anemia. Increased iron requirements to supply the expanding blood volume of the mother and the rapidly growing fetus and placenta can cause IDA. WHO recommends a hemoglobin concentration value of a minimum 11.0 gm% during pregnancy.
 
Maternal iron deficiency anemia early in pregnancy can result in low birth weight subsequent to preterm delivery as well as association exists between maternal anemia and lower infant apgar score. Therefore, iron supplementation is mandatory to improve or maintain the iron status of the mother during pregnancy. Government of India recommends 200 mg of elemental iron with 1mg folic acid in the second half of pregnancy for a period of 100 days. Plenty of oral iron formulations are available.
 
A comparative study was planned to find out the best oral iron supplement for improving iron deficiency anemia in pregnant females as well as to compare their tolerability, as this ultimately influences the patient compliance and the therapeutic outcome. In present study, 2 conventional marketed formulation (ferrous sulphate, ferrous fumarate) are compared with a newer iron supplement (carbonyl iron) in the antenatal women for correction of anemia of pregnancy.
 
Results
Conclusion: Carbonyl iron is effective in the treatment of iron deficiency anemia in pregnant women as compared to the conventional iron formulations because of its superior efficacy in elevating haemoglobin levels as well as it is better tolerated than other iron formulations.

Table 1: Hemoglobin percentage (gm %) at baseline and during the study period
 
References

1 COMPARATIVE STUDY OF IRON SUPPLEMENTS: ITS EFFICACY AND TOLERABILITY
Indian Journal of Basic and Applied Medical Research; September 2015: Vol 4, p. 132-136 Pyarelal, Associate Professor, Department of Pharmacology, MediCiti Institute of Medical Sciences (MIMS), Ghanpur, Telangana Corresponding author: Pyarelal
 
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